Talk:Prepex
Contents |
Possible connections with Bioprotect, Ltd.
The Israeli inventors are affiliated with Bioprotect, which specializes in cheap, mass-produced medical devices. We need to see if there's a connection.--Mazzera 14:46, 16 May 2011 (CDT)
Reference to African RCT's in Patent App
The human immunodeficiency virus (herein abbreviated HIV) is a virus which causes AIDS, a deadly disease which has claimed more than 25 million lives worldwide since its discovery in 1981. Approximately 2 million people worldwide are infected with HIV every year, wherein roughly two thirds of those infected with HIV live in Sub-Saharan Africa. More than 1 million deaths per year occur worldwide as a result of AIDS. Various worldwide attempts to reduce infection and spreading rates of HIV, for example through massive safer sex education programs and free condom distribution points, have not significantly reduced infection rates and can be considered partially successful in reducing the spread of HIV worldwide. Prior art randomized controlled studies as well as epidemiological studies have shown that circumcision can significantly reduce the risk of infection with HIV in males. One possible explanation of the results of such studies is that the skin cells of which the foreskin is constructed have less protection to diseases and infections than skin cells on other parts of the body. Thus, the skin cells of the foreskin are more prone to diseases and infections which may be transmitted by sexual relations when the foreskin is stretched and its skin cells are revealed. Based on these studies, the World Health Organization (known as the WHO) and the Joint United Nations Programme on HIV/AIDS (known as UNAIDS) have published position papers substantially recommending large scale circumcision of adult males worldwide living in regions and amongst populations having higher rates of HIV infection, i.e., HIV at risk regions and populations. These position papers include "Male circumcision: Global trends and determinants of prevalence, safety and acceptability," published by the WHO and UNAIDS in 2007, ISBN 978 92 4 159616 9 (WHO), and "Male Circumcision and HIV Prevention: Research Implications for Policy and Programming - Conclusions and Recommendations," a WHO/UNAIDS Technical Consultation presented in Montreux, Switzerland, on March 6-8, 2007. In addition, other large governmental bodies have put forth possible biological explanations linking circumcision to reduction in HIV infection rate. One such biological explanation can be found on the website of the U.S.'s Centers for Disease Control and Prevention, at http://www.cdc.gov/hiv/resources/factsheets/circumcision.htm. In particular, the published papers of the WHO and the UNAIDS cited research which showed that the risk for infection of HIV is lowered by 44%-71% in circumcised men. The WHO has thus recommended circumcision to be incorporated among the main strategic tools countries and healthcare authorities should consider in order to reduce the spread of HIV.
http://www.wipo.int/pctdb/en/wo.jsp?WO=2011007358&IA=IL2010000568&DISPLAY=DESC
--Mazzera 15:24, 16 May 2011 (CDT)
Safety and Efficacy Study of the PrePex System for Male Circumcision
http://retroconference.org/2011/Abstracts/40740.htm --Mazzera 15:48, 16 May 2011 (CDT)
Circlist Article on PrePex
File:Circlist-the-prepex-device.pdf
News Articles
Nonsurgical Device Effective for Adult Male Circumcision http://www.medscape.com/viewarticle/743451 --Mazzera 22:31, 2 June 2011 (CDT)