Advanced Tissue Sciences

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Advanced Tissue Sciences is a corporation based in La Jolla, CA. They are the makers of Dermagraft-TC, which is an artifical skin created from harvested foreskins from infant circumcision.[1] They are also the makers of NouriCel, another product made from harvested foreskins,[2] and one of the main ingredients of SkinMedica's TNS Recovery Complex product.[3]


Dermagraft-TC is FDA approved,[4][5] and it sells for about $3,000 per square foot and one foreskin contains enough genetic material to grow 250,000 square feet of skin.[6]

Advanced Tissue Sciences has sold about $1 million worth of cultured dermis to Proctor & Gamble, Helene Curtis, and other such businesses for pre-market testing. Advanced Tissue Science's foreskin-derived merchandise held a $32 million stock offering in the beginning of 1992.[7]

In 1996 alone, Advanced Tissue Sciences could boast of a healthy $663.9 million market capitalization performance.[8]


  1. "Dermagraft-TC: Overview". Advanced Biohealing, Inc.. Retrieved 2011-03-06. "Dermagraft is manufactured from human fibroblast cells derived from newborn foreskin tissue." 
  2. "The Foreskin Mafia". Retrieved 2011-03-06. "TNS contains... NouriCel-MD which is... a combination of Natural Growth Factors, matrix proteins, and soluble collagen. Human Growth Factors extracted from cultured cells of foreskin..." 
  3. "SkinMedica Introduces TNS Recovery Complex". SkinMedica. 2002-02-12. Retrieved 2011-03-06. "TNS Recovery Complex is the only product containing a professional concentration of NouriCel®, a new cosmetic ingredient from leading tissue-engineering company Advanced Tissue Sciences." 
  4. "Dermagraft-TC: General Information". Advanced Tissue Sciences. MediLexicon International Ltd. 2011. Retrieved 2011-05-07. "Dermagraft-TC is the first human, fibroblast-derived temporary skin substitute for the treatment of partial-thickness burns that has been approved for marketing by the FDA." 
  5. "Advanced Tissue Sciences' temporary wound covering Dermagraft-TC approved for marketing by FDA". Transplant News. HighBeam Research. 1997-03-28. Retrieved 2011-05-07. "the Food and Drug Administration has approved Dermagraft-TC" 
  6. Circumcision. Daecher M. Icon 1998;2(2):70-3.
  7. Julie Pitta. Biosynthetics. Forbes 10 May 1993: 170-171 Note: The 32-page Advanced Tissue Sciences, Inc. 1997 Annual Report refers to "fibroblasts" but does not contain the word "foreskin."
  8. Biotech's Big Discovery. Hall CT. San Francisco Chronicle. October 25, 1996: E1, E4.
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